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Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

Flaviviruses replicate in membrane factories associated with the endoplasmic reticulum (ER). Significant levels of flavivirus viral protein accumulation contribute to ER stress. As a consequence, the host cell exhibits an Unfolded Protein Response (UPR), subsequently stimulating appropriate cellular...

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Detalles Bibliográficos
Autores principales: Lebeau, Grégorie, Turpin, Jonathan, Frumence, Etienne, El Safadi, Daed, Harrabi, Wissal, Desprès, Philippe, Krejbich-Trotot, Pascale, Viranaïcken, Wildriss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227265/
https://www.ncbi.nlm.nih.gov/pubmed/35746600
http://dx.doi.org/10.3390/v14061131