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Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein
Flaviviruses replicate in membrane factories associated with the endoplasmic reticulum (ER). Significant levels of flavivirus viral protein accumulation contribute to ER stress. As a consequence, the host cell exhibits an Unfolded Protein Response (UPR), subsequently stimulating appropriate cellular...
Autores principales: | Lebeau, Grégorie, Turpin, Jonathan, Frumence, Etienne, El Safadi, Daed, Harrabi, Wissal, Desprès, Philippe, Krejbich-Trotot, Pascale, Viranaïcken, Wildriss |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227265/ https://www.ncbi.nlm.nih.gov/pubmed/35746600 http://dx.doi.org/10.3390/v14061131 |
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