Synthesis and Characterization of Preacinetobactin and 5-Phenyl Preacinetobactin

We report the first total synthesis of 5-phenyl preacinetobactin and its characterization. The route was developed for the synthesis of preacinetobactin, the siderophore critical to the Gram-negative pathogen A. baumannii. It leverages a C5-substituted benzaldehyde as a key starting material and sho...

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Detalles Bibliográficos
Autores principales: Bray, Jean M., Pierce, Scott, Angeles-Boza, Alfredo M., Peczuh, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227331/
https://www.ncbi.nlm.nih.gov/pubmed/35744823
http://dx.doi.org/10.3390/molecules27123688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227331/
https://www.ncbi.nlm.nih.gov/pubmed/35744823
http://dx.doi.org/10.3390/molecules27123688

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