Investigating Potential GLP-1 Receptor Agonists in Cyclopeptides from Pseudostellaria heterophylla, Linum usitatissimum, and Drymaria diandra, and Peptides Derived from Heterophyllin B for the Treatment of Type 2 Diabetes: An In Silico Study

GLP-1 receptor agonists stimulate GLP-1R to promote insulin secretion, whereas DPP4 inhibitors slow GLP-1 degradation. Both approaches are incretin-based therapies for T2D. In addition to GLP-1 analogs, small nonpeptide GLP-1RAs such as LY3502970, TT-OAD2, and PF-06882961 have been considered as pos...

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Detalles Bibliográficos
Autores principales: Liao, Hui-Jun, Tzen, Jason T. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227353/
https://www.ncbi.nlm.nih.gov/pubmed/35736482
http://dx.doi.org/10.3390/metabo12060549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227353/
https://www.ncbi.nlm.nih.gov/pubmed/35736482
http://dx.doi.org/10.3390/metabo12060549

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