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Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation

The success of biotherapeutics is often challenged by the undesirable events of immunogenicity in patients, characterized by the formation of anti-drug antibodies (ADA). Under specific conditions, the ADAs recognizing the biotherapeutic can trigger the formation of immune complexes (ICs), followed b...

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Detalles Bibliográficos
Autores principales: Fichter, Marie, Richter, Gesa, Bepperling, Alexander, Wassmann, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227392/
https://www.ncbi.nlm.nih.gov/pubmed/35745826
http://dx.doi.org/10.3390/pharmaceutics14061254