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Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation
The success of biotherapeutics is often challenged by the undesirable events of immunogenicity in patients, characterized by the formation of anti-drug antibodies (ADA). Under specific conditions, the ADAs recognizing the biotherapeutic can trigger the formation of immune complexes (ICs), followed b...
Autores principales: | Fichter, Marie, Richter, Gesa, Bepperling, Alexander, Wassmann, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227392/ https://www.ncbi.nlm.nih.gov/pubmed/35745826 http://dx.doi.org/10.3390/pharmaceutics14061254 |
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