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A Mathematical Model of In Vitro Cellular Uptake of Zoledronic Acid and Isopentenyl Pyrophosphate Accumulation

The mevalonate pathway is an attractive target for many areas of research, such as autoimmune disorders, atherosclerosis, Alzheimer’s disease and cancer. Indeed, manipulating this pathway results in the alteration of malignant cell growth with promising therapeutic potential. There are several pharm...

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Detalles Bibliográficos
Autores principales: Lo Presti, Elena, D’Orsi, Laura, De Gaetano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227399/
https://www.ncbi.nlm.nih.gov/pubmed/35745834
http://dx.doi.org/10.3390/pharmaceutics14061262