Synthesis and Antileukemia Activity Evaluation of Benzophenanthridine Alkaloid Derivatives

Thirty-three benzophenanthridine alkaloid derivatives (1a–1u and 2a–2l) were synthesized, and their cytotoxic activities against two leukemia cell lines (Jurkat Clone E6-1 and THP-1) were evaluated in vitro using a Cell Counting Kit-8 (CCK-8) assay. Nine of these derivatives (1i–l, 2a, and 2i–l) wit...

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Detalles Bibliográficos
Autores principales: Tang, Yaling, Xu, Xinglian, Li, Jiang, Deng, Lulu, Mu, Shuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227418/
https://www.ncbi.nlm.nih.gov/pubmed/35745057
http://dx.doi.org/10.3390/molecules27123934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227418/
https://www.ncbi.nlm.nih.gov/pubmed/35745057
http://dx.doi.org/10.3390/molecules27123934

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