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Ribotoxic Proteins, Known as Inhibitors of Protein Synthesis, from Mushrooms and Other Fungi According to Endo’s Fragment Detection

rRNA N-glycosylases (EC 3.2.2.22) remove a specific adenine (A(4324), rat 28S rRNA) in the sarcin ricin loop (SRL) involved into ribosome interaction with elongation factors, causing the inhibition of translation, for which they are known as plant ‘ribosome inactivating proteins’ (RIPs). However, pr...

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Detalles Bibliográficos
Autores principales: Landi, Nicola, Hussain, Hafiza Z. F., Pedone, Paolo V., Ragucci, Sara, Di Maro, Antimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227437/
https://www.ncbi.nlm.nih.gov/pubmed/35737065
http://dx.doi.org/10.3390/toxins14060403