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Establishment of a Cre-loxP System Based on a Leaky LAC4 Promoter and an Unstable panARS Element in Kluyveromyces marxianus

The Cre-loxP system produces structural variations, such as deletion, duplication, inversion and translocation, at specific loci and induces chromosomal rearrangements in the genome. To achieve chromosomal rearrangements in Kluyveromyces marxianus, the positions and sequences of centromeres were ide...

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Detalles Bibliográficos
Autores principales: Ren, Haiyan, Yin, Anqi, Wu, Pingping, Zhou, Huanyu, Zhou, Jungang, Yu, Yao, Lu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227491/
https://www.ncbi.nlm.nih.gov/pubmed/35744758
http://dx.doi.org/10.3390/microorganisms10061240