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Comparative Pharmacodynamics of Three Different Botulinum Toxin Type A Preparations following Repeated Intramuscular Administration in Mice

Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily correct spasticity-related disorders and deformities. The paralytic effects of BoNT/A are time-limited and require repeated injections at regula...

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Detalles Bibliográficos
Autores principales: Byun, Jaeyoon, Kwak, Seongsung, Kwon, Jin-Hee, Shin, Minhee, Lee, Dong-Kyu, Rhee, Chang-Hoon, Kang, Won-ho, Oh, Jae-Wook, Cruz, Deu John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227525/
https://www.ncbi.nlm.nih.gov/pubmed/35737026
http://dx.doi.org/10.3390/toxins14060365