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Comparative Pharmacodynamics of Three Different Botulinum Toxin Type A Preparations following Repeated Intramuscular Administration in Mice
Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily correct spasticity-related disorders and deformities. The paralytic effects of BoNT/A are time-limited and require repeated injections at regula...
Autores principales: | Byun, Jaeyoon, Kwak, Seongsung, Kwon, Jin-Hee, Shin, Minhee, Lee, Dong-Kyu, Rhee, Chang-Hoon, Kang, Won-ho, Oh, Jae-Wook, Cruz, Deu John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227525/ https://www.ncbi.nlm.nih.gov/pubmed/35737026 http://dx.doi.org/10.3390/toxins14060365 |
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