Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics

IDP-73152, a novel peptide deformylase inhibitor with an antibacterial effect against Gram-positive bacteria, is in phase I development. The objective of this study was to develop a physiologically-based pharmacokinetic model (PBPK) for IDP-73152 in animals, and to extend the model to humans. Biopha...

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Detalles Bibliográficos
Autores principales: Lee, Myongjae, Jeong, Yoo-Seong, Kim, Min-Soo, An, Kyung-Mi, Chung, Suk-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227536/
https://www.ncbi.nlm.nih.gov/pubmed/35745730
http://dx.doi.org/10.3390/pharmaceutics14061157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227536/
https://www.ncbi.nlm.nih.gov/pubmed/35745730
http://dx.doi.org/10.3390/pharmaceutics14061157

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