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Aspartyl Protease Inhibitors as Anti-Filarial Drugs

The current treatments for lymphatic filariasis and onchocerciasis do not effectively kill the adult parasitic nematodes, allowing these chronic and debilitating diseases to persist in millions of people. Thus, the discovery of new drugs with macrofilaricidal potential to treat these filarial diseas...

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Detalles Bibliográficos
Autores principales: Beld, Liana, Jung, Hyeim, Bulman, Christina A., Rosa, Bruce A., Fischer, Peter U., Janetka, James W., Lustigman, Sara, Sakanari, Judy A., Mitreva, Makedonka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227574/
https://www.ncbi.nlm.nih.gov/pubmed/35745561
http://dx.doi.org/10.3390/pathogens11060707