Cargando…

Hyaluronic Acid-Functionalized Mesoporous Silica Nanoparticles Loading Simvastatin for Targeted Therapy of Atherosclerosis

Atherosclerosis (AS) constitutes a major threat to human health, yet most current therapeutics are hindered in achieving desirable clinical outcomes by low bioavailability or serious side effects. Herein, we constructed an enzyme-responsive and macrophage-targeting drug delivery system (SIM@HA-MSN)...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Kechen, Tang, Zhuang, Song, Zhiling, Meng, Shiyu, Yang, Xiaoxue, Guo, Hui, Zhu, Yizhun, Wang, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227583/
https://www.ncbi.nlm.nih.gov/pubmed/35745836
http://dx.doi.org/10.3390/pharmaceutics14061265