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Electrophile-Dependent Reactivity of Lithiated N-Benzylpyrene-1-Carboxamide

In this paper, we describe the lithiation of N-benzylpyrene-1-carboxamide with RLi-TMEDA. We found that the reaction outcome strongly depends on the electrophile used in the quenching step. The electrophile can be introduced at either the benzylic position or at the C-2 position in the pyrene nucleu...

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Detalles Bibliográficos
Autores principales: Ciechańska, Magdalena, Wrona-Piotrowicz, Anna, Koprowska, Karolina, Makal, Anna, Zakrzewski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227622/
https://www.ncbi.nlm.nih.gov/pubmed/35745055
http://dx.doi.org/10.3390/molecules27123930