A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies

Non-alcoholic fatty liver disease (NAFLD) has a high global prevalence with a heterogeneous and complex pathophysiology that presents barriers to traditional targeted therapeutic approaches. We describe an integrated quantitative systems pharmacology (QSP) platform that comprehensively and unbiasedl...

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Detalles Bibliográficos
Autores principales: Lefever, Daniel E., Miedel, Mark T., Pei, Fen, DiStefano, Johanna K., Debiasio, Richard, Shun, Tong Ying, Saydmohammed, Manush, Chikina, Maria, Vernetti, Lawrence A., Soto-Gutierrez, Alejandro, Monga, Satdarshan P., Bataller, Ramon, Behari, Jaideep, Yechoor, Vijay K., Bahar, Ivet, Gough, Albert, Stern, Andrew M., Taylor, D. Lansing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227696/
https://www.ncbi.nlm.nih.gov/pubmed/35736460
http://dx.doi.org/10.3390/metabo12060528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227696/
https://www.ncbi.nlm.nih.gov/pubmed/35736460
http://dx.doi.org/10.3390/metabo12060528

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