Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish

Manganese neurotoxicity is a hallmark of hypermanganesemia with dystonia 2, an inherited manganese transporter defect caused by mutations in SLC39A14. To identify novel potential targets of manganese neurotoxicity, we performed transcriptome analysis of slc39a14(−/−) mutant zebrafish that were expos...

Descripción completa

Detalles Bibliográficos
Autores principales: Tuschl, Karin, White, Richard J., Trivedi, Chintan, Valdivia, Leonardo E., Niklaus, Stephanie, Bianco, Isaac H., Dadswell, Chris, González-Méndez, Ramón, Sealy, Ian M., Neuhauss, Stephan C. F., Houart, Corinne, Rihel, Jason, Wilson, Stephen W., Busch-Nentwich, Elisabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227717/
https://www.ncbi.nlm.nih.gov/pubmed/35514229
http://dx.doi.org/10.1242/dmm.044594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227717/
https://www.ncbi.nlm.nih.gov/pubmed/35514229
http://dx.doi.org/10.1242/dmm.044594

Ejemplares similares