Specific MRP4 Inhibitor Ceefourin-1 Enhances Apoptosis Induced by 6-Mercaptopurine in Jurkat Leukemic Cells, but Not in Normal Lymphoblast Cell Line CRL-1991

Background and objectives: The multidrug resistance protein 4 (MRP4) is a member of the ABC transporter, which has been extensively related to many types of cancer including leukemia. MRP4 overexpression and activity over the efflux of some chemotherapeutic drugs are the main causes of chemoresistan...

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Detalles Bibliográficos
Autores principales: Becerra, Edgardo, Berumen, Laura, Soto-Ontiveros, Valeria, García-Alcocer, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227748/
https://www.ncbi.nlm.nih.gov/pubmed/35743958
http://dx.doi.org/10.3390/medicina58060695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227748/
https://www.ncbi.nlm.nih.gov/pubmed/35743958
http://dx.doi.org/10.3390/medicina58060695

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