The Release of a Highly Cytotoxic Paullone Bearing a TEMPO Free Radical from the HSA Hydrogel: An EPR Spectroscopic Characterization

This study shows the potential of a thermally induced human serum albumin (HSA) hydrogel to serve as a drug depot for sustained release of a highly cytotoxic modified paullone ligand bearing a TEMPO free radical (HL). The binding of HL to HSA was studied by electron paramagnetic resonance (EPR) spec...

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Detalles Bibliográficos
Autores principales: Vesković, Ana, Nakarada, Đura, Vasiljević, Olga, Dobrov, Anatolie, Spengler, Gabriella, Enyedy, Éva A., Arion, Vladimir B., Popović Bijelić, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227768/
https://www.ncbi.nlm.nih.gov/pubmed/35745747
http://dx.doi.org/10.3390/pharmaceutics14061174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227768/
https://www.ncbi.nlm.nih.gov/pubmed/35745747
http://dx.doi.org/10.3390/pharmaceutics14061174

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