Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria

Antibacterial adjuvants are of great significance, since they allow one to downscale the therapeutic dose of conventional antibiotics and reduce the insurgence of antibacterial resistance. Herein, we report that O-acetylserine sulfhydrylase (OASS) inhibitors could be used as colistin adjuvants to tr...

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Detalles Bibliográficos
Autores principales: Annunziato, Giannamaria, Spadini, Costanza, Marchetti, Marialaura, Franko, Nina, Pavone, Marialaura, Iannarelli, Mattia, Bruno, Agostino, Pieroni, Marco, Bettati, Stefano, Cabassi, Clotilde Silvia, Campanini, Barbara, Costantino, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227781/
https://www.ncbi.nlm.nih.gov/pubmed/35745685
http://dx.doi.org/10.3390/ph15060766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227781/
https://www.ncbi.nlm.nih.gov/pubmed/35745685
http://dx.doi.org/10.3390/ph15060766

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