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L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain

L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential amino acid synthesized by normal cells, but not by neoplastic cells. Adverse effects of L-asparaginase formulations are asso...

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Detalles Bibliográficos
Autores principales: Freitas, Marcela, Souza, Paula, Homem-de-Mello, Mauricio, Fonseca-Bazzo, Yris M., Silveira, Damaris, Ferreira Filho, Edivaldo X., Pessoa Junior, Adalberto, Sarker, Dipak, Timson, David, Inácio, João, Magalhães, Pérola O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227789/
https://www.ncbi.nlm.nih.gov/pubmed/35745665
http://dx.doi.org/10.3390/ph15060746