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L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential amino acid synthesized by normal cells, but not by neoplastic cells. Adverse effects of L-asparaginase formulations are asso...
Autores principales: | Freitas, Marcela, Souza, Paula, Homem-de-Mello, Mauricio, Fonseca-Bazzo, Yris M., Silveira, Damaris, Ferreira Filho, Edivaldo X., Pessoa Junior, Adalberto, Sarker, Dipak, Timson, David, Inácio, João, Magalhães, Pérola O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227789/ https://www.ncbi.nlm.nih.gov/pubmed/35745665 http://dx.doi.org/10.3390/ph15060746 |
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