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Zein-Stabilized Nanospheres as Nanocarriers for Boosting the Aphrodisiac Activity of Icariin: Response Surface Optimization and In Vivo Assessment

Icariin (ICA), a main active compound of the Epimedium genus, is used as an aphrodisiac in traditional Chinese herbal medicine. Despite its therapeutic efficacy, ICA displays reduced oral absorption, and therefore, low bioavailability hindered its clinical application. Implementing nanotechnology in...

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Detalles Bibliográficos
Autores principales: Asfour, Hani Z., Alhakamy, Nabil A., Fahmy, Usama A., Ahmed, Osama A. A., Rizg, Waleed Y., Felimban, Raed I., Abdel-Naim, Ashraf B., Abourehab, Mohammad A. S., Mansouri, Rasha A., Omar, Ulfat M., Badr-Eldin, Shaimaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227839/
https://www.ncbi.nlm.nih.gov/pubmed/35745852
http://dx.doi.org/10.3390/pharmaceutics14061279