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Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors

Paclitaxel is widely used in the treatment of various types of solid malignancies. Paclitaxel-induced peripheral neuropathy (PIPN) is often characterized by burning pain, cold, and mechanical allodynia in patients. Currently, specific pharmacological treatments against PIPN are lacking. Curcumin, a...

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Detalles Bibliográficos
Autores principales: Caillaud, Martial, Thompson, Danielle, Toma, Wisam, White, Alyssa, Mann, Jared, Roberts, Jane L., Bigbee, John W., Gewirtz, David A., Damaj, M. Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227889/
https://www.ncbi.nlm.nih.gov/pubmed/35745868
http://dx.doi.org/10.3390/pharmaceutics14061296