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Assessment of Diverse Solid−State Accelerated Autoxidation Methods for Droperidol

The present study aimed to investigate methods for accelerating autoxidation of crystalline drugs in the solid-state that can potentially predict real−time stability. Solid droperidol (DPD) was selected as the model drug. A common free−radical initiator, 2,2′−azobisisobutyronitrile (AIBN), was used...

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Detalles Bibliográficos
Autores principales: Iyer, Jayant, Saraf, Isha, Ray, Andrew, Brunsteiner, Michael, Paudel, Amrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227907/
https://www.ncbi.nlm.nih.gov/pubmed/35745687
http://dx.doi.org/10.3390/pharmaceutics14061114