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Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension

This study aimed to determine whether adrenomedullin (ADM, 7.2 μg/kg/day, ip), an important endogenous active peptide, has a protective role in cardiac remodeling and function in obesity-related hypertension (OH) rats. A high-fat diet (HFD) was used to induce OH for 20 weeks. H9c2 cells incubated wi...

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Detalles Bibliográficos
Autores principales: Qian, Pei, Wang, Qian, Wang, Fang-Zheng, Dai, Hang-Bing, Wang, Hong-Yu, Gao, Qing, Zhou, Hong, Zhou, Ye-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227996/
https://www.ncbi.nlm.nih.gov/pubmed/35745637
http://dx.doi.org/10.3390/ph15060719