Discovery of Quinazoline-2,4(1H,3H)-Dione Derivatives as Potential Antibacterial Agent: Design, Synthesis, and Their Antibacterial Activity

In this paper, we report on the design and synthesis of a novel series of quinazoline-2,4(1H,3H)-dione derivatives as fluoroquinolone-like inhibitors of bacterial gyrase and DNA topoisomerase IV to identify and develop antimicrobial agents to prevent bacterial resistance problems. Their structures w...

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Detalles Bibliográficos
Autores principales: Boshta, Nader M., El-Essawy, Farag A., Alshammari, Mohammed B., Noreldein, Safaa G., Darwesh, Osama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228007/
https://www.ncbi.nlm.nih.gov/pubmed/35744976
http://dx.doi.org/10.3390/molecules27123853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228007/
https://www.ncbi.nlm.nih.gov/pubmed/35744976
http://dx.doi.org/10.3390/molecules27123853

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