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1,5-Benzothiazepine Derivatives: Green Synthesis, In Silico and In Vitro Evaluation as Anticancer Agents

Considering the importance of benzothiazepine pharmacophore, an attempt was carried out to synthesize novel 1,5-benzothiazepine derivatives using polyethylene glycol-400 (PEG-400)-mediated pathways. Initially, different chalcones were synthesized and then subjected to a cyclization step with benzoth...

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Detalles Bibliográficos
Autores principales: Haroun, Michelyne, Chobe, Santosh S., Alavala, Rajasekhar Reddy, Mathure, Savita M., Jamullamudi, Risy Namratha, Nerkar, Charushila K., Gugulothu, Vijay Kumar, Tratrat, Christophe, Islam, Mohammed Monirul, Venugopala, Katharigatta N., Habeebuddin, Mohammed, Telsang, Mallikarjun, Sreeharsha, Nagaraja, Anwer, Md. Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228089/
https://www.ncbi.nlm.nih.gov/pubmed/35744881
http://dx.doi.org/10.3390/molecules27123757