Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451

A tetrahydroisoquinoline (THIQ) core is able to mimic the A and B rings of 2-methoxyestradiol (2ME2), an endogenous estrogen metabolite that demonstrates promising anticancer properties primarily by disrupting microtubule dynamic instability parameters, but has very poor pharmaceutical properties th...

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Detalles Bibliográficos
Autores principales: Hargrave, Scott D., Joubert, Anna M., Potter, Barry V. L., Dohle, Wolfgang, Marais, Sumari, Mercier, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228122/
https://www.ncbi.nlm.nih.gov/pubmed/35744942
http://dx.doi.org/10.3390/molecules27123819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228122/
https://www.ncbi.nlm.nih.gov/pubmed/35744942
http://dx.doi.org/10.3390/molecules27123819

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