Cargando…

Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451

A tetrahydroisoquinoline (THIQ) core is able to mimic the A and B rings of 2-methoxyestradiol (2ME2), an endogenous estrogen metabolite that demonstrates promising anticancer properties primarily by disrupting microtubule dynamic instability parameters, but has very poor pharmaceutical properties th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hargrave, Scott D., Joubert, Anna M., Potter, Barry V. L., Dohle, Wolfgang, Marais, Sumari, Mercier, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228122/ https://www.ncbi.nlm.nih.gov/pubmed/35744942 http://dx.doi.org/10.3390/molecules27123819

Ejemplares similares

Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines
por: Nel, Marcel, et al.
Publicado: (2018)

Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure
por: Dohle, Wolfgang, et al.
Publicado: (2019)

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
por: Leese, Mathew P., et al.
Publicado: (2011)

Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7
por: Alghanem, Bandar, et al.
Publicado: (2020)

Polyphenols Sensitization Potentiates Susceptibility of MCF-7 and MDA MB-231 Cells to Centchroman
por: Singh, Neetu, et al.
Publicado: (2012)

Antitumor Activity of Chinese Propolis in Human Breast Cancer MCF-7 and MDA-MB-231 Cells
por: Xuan, Hongzhuan, et al.
Publicado: (2014)

Flavokawain A Induces Apoptosis in MCF-7 and MDA-MB231 and Inhibits the Metastatic Process In Vitro
por: Abu, Nadiah, et al.
Publicado: (2014)

Differences in the starvation-induced autophagy response in MDA-MB-231 and MCF-7 breast cancer cells
por: Zhu, Wanyun, et al.
Publicado: (2017)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro
por: Abu, Nadiah, et al.
Publicado: (2016)

Apoptosis Induced by 13-S-hydroxyoctadecadienoic acid in the Breast Cancer Cell Lines, MCF-7 and MDA-MB-231
por: Tavakoli Yaraki, Masoumeh, et al.
Publicado: (2013)

Apoptosis Induced by 13-S-hydroxyoctadecadienoic acid in the Breast Cancer Cell Lines, MCF-7 and MDA-MB-231
por: Tavakoli Yaraki, Masoumeh, et al.
Publicado: (2013)

Differential Epigenetic Effects of Atmospheric Cold Plasma on MCF-7 and MDA-MB-231 Breast Cancer Cells
por: Park, Sung-Bin, et al.
Publicado: (2015)

Evaluation of anticancer potential of Bacopa monnieri L. against MCF-7 and MDA-MB 231 cell line
por: Mallick, Md. Nasar, et al.
Publicado: (2015)

Neem Seed Oil Induces Apoptosis in MCF-7 and MDA MB-231 Human Breast Cancer Cells
por: Sharma, Ramesh, et al.
Publicado: (2017)

Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT–tamoxifen hybrid therapy
por: Theodossiou, Theodossis A., et al.
Publicado: (2019)

Ursolic Acid Enhances the Sensitivity of MCF-7 and MDA-MB-231 Cells to Epirubicin by Modulating the Autophagy Pathway
por: Wang, Zhennan, et al.
Publicado: (2022)

Potential Effects of Chrysin on MDA-MB-231 Cells
por: Hong, Teh Ban, et al.
Publicado: (2010)

Factors modulating integrin Beta I expression on the breast cancer cell lines MCF-7 and MDA-MB-231
por: Pogson, CJ, et al.
Publicado: (2000)

CyclinD1 protein plays different roles in modulating chemoresponses in MCF7 and MDA-MB231 cells
por: Sun, Yuan, et al.
Publicado: (2012)

Effects of combination therapy of docetaxel with selenium on the human breast cancer cell lines MDA-MB-231 and MCF-7
por: Park, Sang O, et al.
Publicado: (2015)

Differential Expression of HSP90β in MDA-MB-231 and MCF-7 Cell Lines after Treatment with Doxorubicin
por: Jokar, Fereshte, et al.
Publicado: (2019)

Use of Selected Carbon Nanoparticles as Melittin Carriers for MCF-7 and MDA-MB-231 Human Breast Cancer Cells
por: Daniluk, Karolina, et al.
Publicado: (2019)

Docetaxel-loaded PLGA nanoparticles to increase pharmacological sensitivity in MDA-MB-231 and MCF-7 breast cancer cells
por: Tran, Phuong, et al.
Publicado: (2021)

Allium willeanum Holmboe exerts anticancer activities on metastatic breast cancer cells MCF-7 and MDA-MB-231
por: Isbilen, Ovgu, et al.
Publicado: (2021)

Differential response of MDA‑MB‑231 breast cancer and MCF10A normal breast cells to cytoskeletal disruption
por: Kwon, Sangwoo, et al.
Publicado: (2023)

Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
por: You, Mi-Kyoung, et al.
Publicado: (2016)

Citral induced apoptosis in MDA-MB-231 spheroid cells
por: Nigjeh, Siyamak Ebrahimi, et al.
Publicado: (2018)

Shock wave impact on the viability of MDA-MB-231 cells
por: Liao, Yingqian, et al.
Publicado: (2020)

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR
por: An, Jiaqiang, et al.
Publicado: (2017)

Temporin-GHb of Hylarana guentheri induces apoptosis by the mitochondrial pathway in MDA-MB-231 cells : Temporin-GHb induces MDA-MB-231 cell apoptosis
por: Liu, Yujun, et al.
Publicado: (2022)

Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells
por: Zhang, Zhongyuan, et al.
Publicado: (2013)

Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells
por: Kianpour Rad, Sima, et al.
Publicado: (2015)

Analysis of Protein–Protein Interactions in MCF-7 and MDA-MB-231 Cell Lines Using Phthalic Acid Chemical Probes
por: Liang, Shih-Shin, et al.
Publicado: (2014)

Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231
por: Tenorio, María J., et al.
Publicado: (2016)

Withaferin A Induces ROS-Mediated Paraptosis in Human Breast Cancer Cell-Lines MCF-7 and MDA-MB-231
por: Ghosh, Kamalini, et al.
Publicado: (2016)

The Impact of Soy Isoflavones on MCF-7 and MDA-MB-231 Breast Cancer Cells Using a Global Metabolomic Approach
por: Uifălean, Alina, et al.
Publicado: (2016)

Comparing Apoptosis and Necrosis Effects of Arctium Lappa Root Extract and Doxorubicin on MCF7 and MDA-MB-231 Cell Lines
por: Ghafari, Fereshteh, et al.
Publicado: (2017)

Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231
por: Garbar, Christian, et al.
Publicado: (2017)

Nuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells
por: Nehdi, Atef, et al.
Publicado: (2019)

Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
por: Konieczna, Natalia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_sbc5pmb5u8inhnms852f5q9iiu