SARS-CoV-2 Delta Variant N Gene Mutations Reduce Sensitivity to the TaqPath COVID-19 Multiplex Molecular Diagnostic Assay

As the SARS-CoV-2 virus evolves, mutations may result in diminished sensitivity to qRT-PCR diagnostic assays. We investigated four polymorphisms circulating in the SARS-CoV-2 Delta lineage that result in N gene target failure (NGTF) on the TaqPath COVID-19 Combo Kit. These mutations were detected fr...

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Detalles Bibliográficos
Autores principales: Holland, Steven C., Bains, Ajeet, Holland, LaRinda A., Smith, Matthew F., Sullins, Regan A., Mellor, Nicholas J., Thomas, Alexis W., Johnson, Nathaniel, Murugan, Vel, Lim, Efrem S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228125/
https://www.ncbi.nlm.nih.gov/pubmed/35746787
http://dx.doi.org/10.3390/v14061316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228125/
https://www.ncbi.nlm.nih.gov/pubmed/35746787
http://dx.doi.org/10.3390/v14061316

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