New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase

To develop novel chemotherapeutic alternatives for the treatment of Chagas disease, in this study, a set of new amino naphthoquinone derivatives were synthesised and evaluated in vitro on the epimastigote and trypomastigote forms of Trypanosoma cruzi strains (NINOA and INC-5) and on J774 murine macr...

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Detalles Bibliográficos
Autores principales: Espinosa-Bustos, Christian, Ortiz Pérez, Mariana, Gonzalez-Gonzalez, Alonzo, Zarate, Ana María, Rivera, Gildardo, Belmont-Díaz, Javier A., Saavedra, Emma, Cuellar, Mauricio A., Vázquez, Karina, Salas, Cristian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228152/
https://www.ncbi.nlm.nih.gov/pubmed/35745694
http://dx.doi.org/10.3390/pharmaceutics14061121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228152/
https://www.ncbi.nlm.nih.gov/pubmed/35745694
http://dx.doi.org/10.3390/pharmaceutics14061121

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