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An Integrated Mass Spectrometry-Based Glycomics-Driven Glycoproteomics Analytical Platform to Functionally Characterize Glycosylation Inhibitors

Cancer progression is linked to aberrant protein glycosylation due to the overexpression of several glycosylation enzymes. These enzymes are underexploited as potential anticancer drug targets and the development of rapid-screening methods and identification of glycosylation inhibitors are highly so...

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Detalles Bibliográficos
Autores principales: Alvarez, Michael Russelle S., Zhou, Qingwen, Grijaldo, Sheryl Joyce B., Lebrilla, Carlito B., Nacario, Ruel C., Heralde, Francisco M., Rabajante, Jomar F., Completo, Gladys C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228227/
https://www.ncbi.nlm.nih.gov/pubmed/35744954
http://dx.doi.org/10.3390/molecules27123834