QSAR, ADMET In Silico Pharmacokinetics, Molecular Docking and Molecular Dynamics Studies of Novel Bicyclo (Aryl Methyl) Benzamides as Potent GlyT1 Inhibitors for the Treatment of Schizophrenia

Forty-four bicyclo ((aryl) methyl) benzamides, acting as glycine transporter type 1 (GlyT1) inhibitors, are developed using molecular modeling techniques. QSAR models generated by multiple linear and non-linear regressions affirm that the biological inhibitory activity against the schizophrenia dise...

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Detalles Bibliográficos
Autores principales: El fadili, Mohamed, Er-Rajy, Mohammed, Kara, Mohammed, Assouguem, Amine, Belhassan, Assia, Alotaibi, Amal, Mrabti, Nidal Naceiri, Fidan, Hafize, Ullah, Riaz, Ercisli, Sezai, Zarougui, Sara, Elhallaoui, Menana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228289/
https://www.ncbi.nlm.nih.gov/pubmed/35745588
http://dx.doi.org/10.3390/ph15060670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228289/
https://www.ncbi.nlm.nih.gov/pubmed/35745588
http://dx.doi.org/10.3390/ph15060670

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