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Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography

Analysis of protein glycosylation is challenging due to micro- and macro-heterogeneity of the attached glycans. Hydrophilic interaction liquid chromatography (HILIC) is a mode of choice for separation of intact glycopeptides, which are inadequately resolved by reversed phase chromatography. In this...

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Detalles Bibliográficos
Autores principales: Kozlik, Petr, Molnarova, Katarina, Jecmen, Tomas, Krizek, Tomas, Bosakova, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228347/
https://www.ncbi.nlm.nih.gov/pubmed/35744847
http://dx.doi.org/10.3390/molecules27123723