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Longitudinal Consumption of Ergothioneine Reduces Oxidative Stress and Amyloid Plaques and Restores Glucose Metabolism in the 5XFAD Mouse Model of Alzheimer’s Disease

Background: Ergothioneine (ERGO) is a unique antioxidant and a rare amino acid available in fungi and various bacteria but not in higher plants or animals. Substantial research data indicate that ERGO is a physiological antioxidant cytoprotectant. Different from other antioxidants that need to breac...

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Detalles Bibliográficos
Autores principales: Whitmore, Clayton A., Haynes, Justin R., Behof, William J., Rosenberg, Adam J., Tantawy, Mohammed N., Hachey, Brian C., Wadzinski, Brian E., Spiller, Benjamin W., Peterson, Todd E., Paffenroth, Krista C., Harrison, Fiona E., Beelman, Robert B., Wijesinghe, Printha, Matsubara, Joanne A., Pham, Wellington
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228400/
https://www.ncbi.nlm.nih.gov/pubmed/35745661
http://dx.doi.org/10.3390/ph15060742