Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors

Protein arginine methyltransferase 5 (PRMT5) is an attractive molecular target in anticancer drug discovery due to its extensive involvement in transcriptional control, RNA processing, and other cellular pathways that are causally related to tumor initiation and progression. In recent years, various...

Descripción completa

Detalles Bibliográficos
Autores principales: Brown, Tyler, Cao, Mengtong, Zheng, Y. George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228412/
https://www.ncbi.nlm.nih.gov/pubmed/35744905
http://dx.doi.org/10.3390/molecules27123779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228412/
https://www.ncbi.nlm.nih.gov/pubmed/35744905
http://dx.doi.org/10.3390/molecules27123779

Ejemplares similares