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Reconstruction of the Genome-Scale Metabolic Model of Saccharopolyspora erythraea and Its Application in the Overproduction of Erythromycin

Saccharopolyspora erythraea is considered to be an effective host for erythromycin. However, little is known about the regulation in terms of its metabolism. To develop an accurate model-driven strategy for the efficient production of erythromycin, a genome-scale metabolic model (iJL1426) was recons...

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Detalles Bibliográficos
Autores principales: Xu, Feng, Lu, Ju, Ke, Xiang, Shao, Minghao, Huang, Mingzhi, Chu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228414/
https://www.ncbi.nlm.nih.gov/pubmed/35736442
http://dx.doi.org/10.3390/metabo12060509