Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity

Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like symptoms. Our previous research suggests that mercury levels are directly associated with ALS progression. MeHg+-induced ALS is char...

Descripción completa

Detalles Bibliográficos
Autores principales: Shandilya, Ambika, Mehan, Sidharth, Kumar, Sumit, Sethi, Pranshul, Narula, Acharan S., Alshammari, Abdulrahman, Alharbi, Metab, Alasmari, Abdullah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228431/
https://www.ncbi.nlm.nih.gov/pubmed/35745001
http://dx.doi.org/10.3390/molecules27123878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228431/
https://www.ncbi.nlm.nih.gov/pubmed/35745001
http://dx.doi.org/10.3390/molecules27123878

Ejemplares similares