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Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity
Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like symptoms. Our previous research suggests that mercury levels are directly associated with ALS progression. MeHg+-induced ALS is char...
Autores principales: | Shandilya, Ambika, Mehan, Sidharth, Kumar, Sumit, Sethi, Pranshul, Narula, Acharan S., Alshammari, Abdulrahman, Alharbi, Metab, Alasmari, Abdullah F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228431/ https://www.ncbi.nlm.nih.gov/pubmed/35745001 http://dx.doi.org/10.3390/molecules27123878 |
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