Facile Preparation of UFMylation Activity-Based Probes by Chemoselective Installation of Electrophiles at the C-Terminus of Recombinant UFM1

[Image: see text] Aberrations in protein modification with ubiquitin-fold modifier (UFM1) are associated with a range of diseases, but the biological function and regulation of this post-translational modification, known as UFMylation, remain enigmatic. To provide activity-based probes for UFMylatio...

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Detalles Bibliográficos
Autores principales: Tolmachova, Kateryna A., Farnung, Jakob, Liang, Jin Rui, Corn, Jacob E., Bode, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228560/
https://www.ncbi.nlm.nih.gov/pubmed/35756382
http://dx.doi.org/10.1021/acscentsci.2c00203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228560/
https://www.ncbi.nlm.nih.gov/pubmed/35756382
http://dx.doi.org/10.1021/acscentsci.2c00203

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