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Facile Preparation of UFMylation Activity-Based Probes by Chemoselective Installation of Electrophiles at the C-Terminus of Recombinant UFM1
[Image: see text] Aberrations in protein modification with ubiquitin-fold modifier (UFM1) are associated with a range of diseases, but the biological function and regulation of this post-translational modification, known as UFMylation, remain enigmatic. To provide activity-based probes for UFMylatio...
Autores principales: | Tolmachova, Kateryna A., Farnung, Jakob, Liang, Jin Rui, Corn, Jacob E., Bode, Jeffrey W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228560/ https://www.ncbi.nlm.nih.gov/pubmed/35756382 http://dx.doi.org/10.1021/acscentsci.2c00203 |
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