Ratios of Acetaminophen Metabolites Identify New Loci of Pharmacogenetic Relevance in a Genome-Wide Association Study

Genome-wide association studies (GWAS) with non-targeted metabolomics have identified many genetic loci of biomedical interest. However, metabolites with a high degree of missingness, such as drug metabolites and xenobiotics, are often excluded from such studies due to a lack of statistical power an...

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Detalles Bibliográficos
Autores principales: Thareja, Gaurav, Evans, Anne M., Wood, Spencer D., Stephan, Nisha, Zaghlool, Shaza, Halama, Anna, Kastenmüller, Gabi, Belkadi, Aziz, Albagha, Omar M. E., Suhre, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228664/
https://www.ncbi.nlm.nih.gov/pubmed/35736429
http://dx.doi.org/10.3390/metabo12060496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228664/
https://www.ncbi.nlm.nih.gov/pubmed/35736429
http://dx.doi.org/10.3390/metabo12060496

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