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The Therapeutic Role of PNU-74654 in Hepatocellular Carcinoma May Involve Suppression of NF-κB Signaling

Background and Objectives: PNU-74654, a Wnt/β-catenin inhibitor, has reported antitumor activities; however, the therapeutic potential of PNU-74654 in hepatocellular carcinoma (HCC) has not been investigated in detail. The aim of this study was to clarify the cytotoxic effects of PNU-74654 against H...

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Detalles Bibliográficos
Autores principales: Wu, Min-You, Wang, Chi-Chih, Chang, Ya-Chuan, Yu, Chia-Ying, Sung, Wen-Wei, Chen, Chih-Jung, Tsai, Ming-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228701/
https://www.ncbi.nlm.nih.gov/pubmed/35744061
http://dx.doi.org/10.3390/medicina58060798