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Tigecycline and Gentamicin-Combined Treatment Enhances Renal Damage: Oxidative Stress, Inflammatory Reaction, and Apoptosis Interplay

Although the combination of antibiotics is generally well-tolerated, they may have nephrotoxic effects. This study investigated whether tigecycline (TG) and gentamicin (GM) co-administration could accelerate renal damage. Male Wistar rats were randomly divided into six experimental groups: the contr...

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Detalles Bibliográficos
Autores principales: Elgazzar, Dina, Aboubakr, Mohamed, Bayoumi, Heba, Ibrahim, Amany N., Sorour, Safwa M., El-Hewaity, Mohamed, Elsayed, Abulmaaty M., Shehata, Shaimaa A., Bayoumi, Khaled A., Alsieni, Mohammed, Behery, Maged, Abdelrahaman, Doaa, Ibrahim, Samah F., Abdeen, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228782/
https://www.ncbi.nlm.nih.gov/pubmed/35745655
http://dx.doi.org/10.3390/ph15060736