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Tigecycline and Gentamicin-Combined Treatment Enhances Renal Damage: Oxidative Stress, Inflammatory Reaction, and Apoptosis Interplay
Although the combination of antibiotics is generally well-tolerated, they may have nephrotoxic effects. This study investigated whether tigecycline (TG) and gentamicin (GM) co-administration could accelerate renal damage. Male Wistar rats were randomly divided into six experimental groups: the contr...
Autores principales: | Elgazzar, Dina, Aboubakr, Mohamed, Bayoumi, Heba, Ibrahim, Amany N., Sorour, Safwa M., El-Hewaity, Mohamed, Elsayed, Abulmaaty M., Shehata, Shaimaa A., Bayoumi, Khaled A., Alsieni, Mohammed, Behery, Maged, Abdelrahaman, Doaa, Ibrahim, Samah F., Abdeen, Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228782/ https://www.ncbi.nlm.nih.gov/pubmed/35745655 http://dx.doi.org/10.3390/ph15060736 |
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