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High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4(+) T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19

Here, we longitudinally assessed the ex vivo frequency and phenotype of SARS-CoV-2 membrane protein (aa145–164) epitope-specific CD4(+) T-cells of an anti-CD20-treated patient with prolonged viral positivity in direct comparison to an immunocompetent patient through an MHC class II DRB1*11:01 Tetram...

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Detalles Bibliográficos
Autores principales: Cords, Leon, Knapp, Maximilian, Woost, Robin, Schulte, Sophia, Kummer, Silke, Ackermann, Christin, Beisel, Claudia, Peine, Sven, Johansson, Alexandra Märta, Kwok, William Wai-Hung, Günther, Thomas, Fischer, Nicole, Wittner, Melanie, Addo, Marylyn Martina, Huber, Samuel, Schulze zur Wiesch, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228841/
https://www.ncbi.nlm.nih.gov/pubmed/35746736
http://dx.doi.org/10.3390/v14061265