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Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery
Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration. Typical intestinal efflux transporters involved in oral drug a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228857/ https://www.ncbi.nlm.nih.gov/pubmed/35745704 http://dx.doi.org/10.3390/pharmaceutics14061131 |