Cargando…

Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery

Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration. Typical intestinal efflux transporters involved in oral drug a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Rong, Zhou, Yun, Ma, Jinqian, Wang, Yuchen, Miao, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228857/
https://www.ncbi.nlm.nih.gov/pubmed/35745704
http://dx.doi.org/10.3390/pharmaceutics14061131