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Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation

The development of new bioactive compounds represents one of the main purposes of the drug discovery process. Various tools can be employed to identify new drug candidates against pharmacologically relevant biological targets, and the search for new approaches and methodologies often represents a cr...

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Detalles Bibliográficos
Autores principales: Gazzillo, Erica, Terracciano, Stefania, Ruggiero, Dafne, Potenza, Marianna, Chini, Maria Giovanna, Lauro, Gianluigi, Fischer, Katrin, Hofstetter, Robert Klaus, Giordano, Assunta, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228872/
https://www.ncbi.nlm.nih.gov/pubmed/35744994
http://dx.doi.org/10.3390/molecules27123866